Quantity: 100 μg
MW: 21 kDa
Source: E. coliderived
Accession # NP_P62256
Stock: X μg/μg in 50 mM PBS pH 7.3 1mM DTT
Purity: >95%, by SDS-PAGE
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UBE2H/UbcH2
| 產(chǎn)品編號 | 規(guī)格 | 價(jià)格 | 貨期 | |
| UBE-607 | 100μg | ￥1280 | 現(xiàn)貨 |
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Ubiquitin-conjugating Enzyme H2 (UbcH2), also known as Ubiquitin-conjugating Enzyme E2H (UBE2H), is a member of the Ubiquitin-conjugating (E2) enzyme family. UbcH2/UBE2H has a predicted molecular weight of 20.5 kDa. The human protein shares 100% amino acid sequence identity with the mouse and rat orthologs. Human UbcH2/UBE2H is highly expressed in skeletal and cardiac muscle, shows significant expression levels in kidney and placenta, and is expressed at low levels in liver, brain, lung, and spleen. TNF-alpha induces UbcH2/UBE2H expression via NF-κB, and SCL/Tal1 upregulates the expression of UbcH2/UBE2H during erythroid differentiation. Pathologically, a single nucleotide polymorphism within UbcH2/UBE2H is associated with autism. Furthermore, UbcH2/UBE2H has been reported as a putative oncogene for liver tumorigenesis.