重組人泛素蛋白
泛素是一個含有76個氨基酸的存在于細胞核和細胞質中的高度保守的蛋白質。泛素只存在于真核細胞中,在泛素蛋白酶體通路(UPP)中,通過酶的作用能夠與底物蛋白供價結合。泛素蛋白的氨基酸序列如下:MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG
Ubiquitin
Ubiquitin is a 76 amino acid, highly conserved nuclear and cytoplasmic protein. It is found exclusively in eukaryotes, becomes covalently attached to substrate proteins by enzymes in the Ubiquitin-Proteosome Pathway (UPP) and has a major role in targeting cellular proteins for the ATP-dependent degradation by the 26S proteosome. Ubiquitination also affects proteosome-independent events such as protein localization, activity and function.
Sequence in amino acid abbreviations is MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG